Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Review, H2 2016

 

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Abstract

 
Relapsing-remitting multiple sclerosis (RRMS) is the most common form of multiple sclerosis (MS). In RRMS, there are clear episodes of inflammatory activity (relapses). During a period of acute inflammation, old symptoms may worsen and new symptoms may appear. A relapse is when active inflammation, and the resulting symptoms, last more than 24 hours. Symptoms include tingling or numbness, double vision, fatigue, urinary urgency and weakness. Treatment includes corticosteroids and immunoglobulin therapy.  

Description

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Review, H2 2016, provides an overview of the Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) pipeline landscape.

Relapsing-remitting multiple sclerosis (RRMS) is the most common form of multiple sclerosis (MS). In RRMS, there are clear episodes of inflammatory activity (relapses). During a period of acute inflammation, old symptoms may worsen and new symptoms may appear. A relapse is when active inflammation, and the resulting symptoms, last more than 24 hours. Symptoms include tingling or numbness, double vision, fatigue, urinary urgency and weakness. Treatment includes corticosteroids and immunoglobulin therapy.
 

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Report Source Information

Supplied by: Research and Experts 
Date Published: 2016-10-12 

Report: Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Review, H2 2016

 

Contents

Table of Contents
Table of Contents 2
Introduction 5
Relapsing Remitting Multiple Sclerosis (RRMS) Overview 6
Therapeutics Development 7
Relapsing Remitting Multiple Sclerosis (RRMS) - Therapeutics under Development by Companies 9
Relapsing Remitting Multiple Sclerosis (RRMS) - Therapeutics under Investigation by Universities/Institutes 11
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Products Glance 12
Relapsing Remitting Multiple Sclerosis (RRMS) - Products under Development by Companies 15
Relapsing Remitting Multiple Sclerosis (RRMS) - Products under Investigation by Universities/Institutes 17
Relapsing Remitting Multiple Sclerosis (RRMS) - Companies Involved in Therapeutics Development 18
Relapsing Remitting Multiple Sclerosis (RRMS) - Therapeutics Assessment 45
Drug Profiles 59
Relapsing Remitting Multiple Sclerosis (RRMS) - Dormant Projects 168
Relapsing Remitting Multiple Sclerosis (RRMS) - Discontinued Products 170
Relapsing Remitting Multiple Sclerosis (RRMS) - Product Development Milestones 171
Appendix 185
 

List of Tables

List of Tables
Number of Products under Development for Relapsing Remitting Multiple Sclerosis (RRMS), H2 2016 12
Number of Products under Development for Relapsing Remitting Multiple Sclerosis (RRMS) - Comparative Analysis, H2 2016 13
Number of Products under Development by Companies, H2 2016 14
Number of Products under Development by Companies, H2 2016 (Contd..1) 15
Number of Products under Investigation by Universities/Institutes, H2 2016 16
Comparative Analysis by Late Stage Development, H2 2016 17
Comparative Analysis by Clinical Stage Development, H2 2016 18
Comparative Analysis by Early Stage Development, H2 2016 19
Products under Development by Companies, H2 2016 20
Products under Development by Companies, H2 2016 (Contd..1) 21
Products under Investigation by Universities/Institutes, H2 2016 22
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by AB Science SA, H2 2016 23
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by AbbVie Inc, H2 2016 24
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Actelion Ltd, H2 2016 25
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Alkermes Plc, H2 2016 26
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Amarna Therapeutics B.V., H2 2016 27
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Antisense Therapeutics Limited, H2 2016 28
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Biocon Limited, H2 2016 29
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Biogen Inc, H2 2016 30
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Cognosci, Inc., H2 2016 31
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Coherus BioSciences, Inc., H2 2016 32
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Forward Pharma A/S, H2 2016 33
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by GeNeuro SA, H2 2016 34
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by GlaxoSmithKline Plc, H2 2016 35
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Iltoo Pharma, H2 2016 36
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by LFB S.A., H2 2016 37
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Mapi Pharma Ltd., H2 2016 38
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by MedImmune, LLC, H2 2016 39
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Merck KGaA, H2 2016 40
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Mitsubishi Tanabe Pharma Corporation, H2 2016 41
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Neurotec Pharma SL, H2 2016 42
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Novartis AG, H2 2016 43
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Octapharma AG, H2 2016 44
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Opexa Therapeutics, Inc., H2 2016 45
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by RedHill Biopharma Ltd., H2 2016 46
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Teva Pharmaceutical Industries Ltd., H2 2016 47
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Xenetic Biosciences (UK) Limited, H2 2016 48
Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline by Zydus Cadila Healthcare Limited, H2 2016 49
Assessment by Monotherapy Products, H2 2016 50
Assessment by Combination Products, H2 2016 51
Number of Products by Stage and Target, H2 2016 53
Number of Products by Stage and Mechanism of Action, H2 2016 57
Number of Products by Stage and Route of Administration, H2 2016 61
Number of Products by Stage and Molecule Type, H2 2016 63
Relapsing Remitting Multiple Sclerosis (RRMS) - Dormant Projects, H2 2016 173
Relapsing Remitting Multiple Sclerosis (RRMS) - Dormant Projects (Contd..1), H2 2016 174
Relapsing Remitting Multiple Sclerosis (RRMS) - Discontinued Products, H2 2016 175
 

List of Figures

List of Figures
Number of Products under Development for Relapsing Remitting Multiple Sclerosis (RRMS), H2 2016 12
Number of Products under Development for Relapsing Remitting Multiple Sclerosis (RRMS) - Comparative Analysis, H2 2016 13
Number of Products under Development by Companies, H2 2016 14
Number of Products under Investigation by Universities/Institutes, H2 2016 16
Comparative Analysis by Late Stage Development, H2 2016 17
Comparative Analysis by Clinical Stage Development, H2 2016 18
Comparative Analysis by Early Stage Products, H2 2016 19
Assessment by Monotherapy Products, H2 2016 50
Number of Products by Top 10 Targets, H2 2016 52
Number of Products by Stage and Top 10 Targets, H2 2016 52
Number of Products by Top 10 Mechanism of Actions, H2 2016 56
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2016 56
Number of Products by Routes of Administration, H2 2016 60
Number of Products by Stage and Routes of Administration, H2 2016 60
Number of Products by Top 10 Molecule Types, H2 2016 62
Number of Products by Stage and Top 10 Molecule Types, H2 2016 62
 

Scope


- The pipeline guide provides a snapshot of the global therapeutic landscape of Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System).
- The pipeline guide reviews pipeline therapeutics for Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
- The pipeline guide reviews latest news related to pipeline therapeutics for Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System)

 

Highlights

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Review, H2 2016, provides comprehensive information on the therapeutics under development for Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Relapsing Remitting Multiple Sclerosis (RRMS) and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical and Discovery stages are 4, 5, 18, 1, 6 and 1 respectively for Similarly, the Universities portfolio in Phase II and Phase I stages comprises 1 and 1 molecules, respectively for Relapsing Remitting Multiple Sclerosis (RRMS).

Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

 

Classification

Language Code: EN 
Region: Global 
Report Type: Market Report 
Industry: Life Sciences 
Sector: Central Nervous System 
Pages: 191 

Companies Featured

AB Science SA AbbVie Inc Actelion Ltd Alkermes Plc Amarna Therapeutics B.V. Antisense Therapeutics Limited Biocon Limited Biogen Inc Cognosci, Inc. Coherus BioSciences, Inc. Forward Pharma A/S GeNeuro SA GlaxoSmithKline Plc Iltoo Pharma LFB S.A. Mapi Pharma Ltd. MedImmune, LLC Merck KGaA Mitsubishi Tanabe Pharma Corporation Neurotec Pharma SL Novartis AG Octapharma AG Opexa Therapeutics, Inc. RedHill Biopharma Ltd. Teva Pharmaceutical Industries Ltd. Xenetic Biosciences (UK) Limited Zydus Cadila Healthcare Limited

 

Reasons to buy this report


- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it's most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Relapsing Remitting Multiple Sclerosis (RRMS) (Central Nervous System) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
 

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Relapsing Remitting Multiple Sclerosis (RRMS) - Pipeline Review, H2 2016

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The global economy is the economy of all the world's countries. The total world population now stands at over 7 billion and the global unemployment rate is 9% with approximately half the world's population paid less than $2 a day. 

The global economy is picking up again after five years of uncertaintity and slow economic growth. The IMF is predicting global growth of 3.7% in 2014 rising to 3.9% in 2015. However, much uncertainity remains. Low inflation in developed economies means that these economies take longer to deal with debt burdens and are at increases risk of deflation. 

The second half of 2013 saw growth in the US and European economies (particularly UK, Germany and France).  

Growth in the US has been helped by cheaper energy from fracking , renewables and more oil and gas exploration. This cheaper energy is bring manufacturing jobs back to the US and helping to boost domestic demand. Recent winter weather conditions have hampered growth in the construction sector and have slowed demand in the construction equipment sector which saw exports drop by 25% in 2013. Growth should pick up in this sector with continued federal investment in infrastructure, new residential house builds and refurbishment and the energy boom.

In Europe growth is expected to be uneven with growth being slow in stressed economies such as Portugal and Greece but confidence picking up in UK, Ireland and even Spain showing some improvement.

Developing economies such as China and India will continue to have strong growth in 2014 and 2015. China has benefitted from increased investment with the Chinese govenment now focused on quality growth of 7.5% in 2014. India which is less reliant on exports expects growth of 5.4% in 2014 and 6.4% in 2015.

Much uncertainity still remains in the global economy with greater optimism needed to stabilise growth.

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Central Nervous System

Central Nervous System

 

Healthcare

The healthcare industry is changing rapidly due to changes in legislation (US Affordable Healthcare Act),  advances in IT and more pressures on governments and healthcare providers due to rising costs. 

According to a recent report by the OECD healthcare spending has fallen in one third of OECD member states due to the credit crunch and members are facing up to the challenge of providing greater care with fewer resources. Spending on healthcare has increased in Japan, Israel and Korea while it has dropped dramatically in Greece and Ireland.

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The Life Sciences industry includes biotechnology, healthcare, pharmaceuticals, medical devices and diagnostics. The industry is dominated by US companies requiring considerable investment in research and development to stay competitive.  While US companies dominate this space, competition is emerging from smaller companies in Europe and Asia. 

Companies trying to stay competitive or enter new markets in life sciences consult our reports. For example, Plimsoll, in their recent review of global antibiotic manufacturers have reviewed 150 of the largest manufacturers including analysis of  ANTIBIOTICE SA, BAYER HEALTHCARE MANUFACTURING SRL and CIPLA LTD. 

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